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The Cell – Inner Boundaries
Membranes and Transport


System requirements: Windows 95/98/ME/NT4/2000/XP,
MacOS 8.1 or higher
Price: 34,95 Euros (incl. VAT, countries other than Germany: + actual shipping costs + 5 Euros flat rate for service)
Order: The English version can only be ordered directly from the IWF Knowledge and Media. Notice: Copies of the English version do not include an information booklet.
The German version can be ordered over book shops (ISBN 3-494-01309-8) or by direct order at IWF Knowledge and Media.

Membranes control the exchange of materials with the cell's surroundings and divide the interior of the cell into different compartments, such as Golgi apparatus or endoplasmic reticulum, where specific biochemical reactions take place. The basic characteristics of membranes as well as their functions are described in detail by computer animation and both 2D and 3D graphics. Interactive laboratory experiments lead to in-depth knowledge about the general composition of membranes and about processes such as diffusion, osmosis or volume regulation. 3D animations and numerous video films are used to illustrate the dynamic nature of membrane organisation within cells.


Content

Compass
The compass, which you can access at all times, gives a complete overview of the content. There you find all topics and subjects which you can call upon and deal with.

Compass
Membranes General topics
This chapter informs on the characteristics of biomembranes. 2D and 3D animations explain e.g. the structure of phospholipids as important membrane components or structure and function of proteins (pores, channels, receptors) embedded inside the membrane.


Membrane proteins
Cell membranes
Here plasma membrane, Golgi zone and endoplasmic reticulum are dealt with.
Plasma membrane: Numerous 2D animations and microscopic shots show the complex and manifold functions as barrier-and transport function, pump mechanisms at membranes, receptor functions, signal transmission as well as signal propagation. In a laboratory concerned with the topic of "Cell volume regulation" there are different objects to examine. Electron microscopical images show the different forms of surface structures of epithelial cells, EM shots and graphics inform on the different cell junctions such as desmosomes, gap junctions and tight junctions.
3D models and animations, fluorescence and electron microscopical shots provide you with insights into the fine structure and function of the Golgi apparatus.
The special structural characteristics of the endoplasmic reticulum as well as on its distribution within the cell are demonstrated in fluorescence and light microscopic shots; 2D animations inform on the individual steps of protein synthesis and show how the proteins move from the ER to the Golgi apparatus. Fluorescence shots give evidence on the function of the ER as a calcium depot.


Volume regulation

Neuromuscular junction

Bacteriorhodopsin

Surface structures

Chemotaxis

Action potential

Structure of the Golgi apparatus

Protein sorting
 



Specialities Membranes main menu
The membrane main menu gives an overview of the membrane systems of the cell. You learn how substances are transported between the individual membrane compartments in the cell and out of the cell. Six 3D animations can be chosen and show details of processes such as phagocytosis, endocytosis or exocytosis.



Membranes main menu
Virtual lab
Proof of the bilayer structure of membranes

In this experiment you are to test the hypothesis that intact membranes consist of a double layer of phospholipids. In the first part of the experiment the total surface area of the membranes used in the experiment has to be calculated. After having broken the membranes down into individual phospholipid molecules you determine with the help of the the Langmuir balance how large the surface is that is covered by the monomolecular phospholipid layer.



Lipid bilayer
Diffusion and osmosis
The aim of this experiment is to measure the pure diffusion potential of a cell as a function of the external medium.
Additionally several animations explain the physical basics of the diffusion potential: free diffusion, diffusion barrier, diffusion potential, voltage-driven ion transport (electrophoresis), osmosis, turgor and ion transport in living cells.




Diffusion potential



Electrophoresis
Films
All the films of the learning program are listed and can be accessed individually.



Films
Quiz
The Quiz gives you the opportunity to test your acquired knowledge in structure and function of membranes as well as the outcomes of the experiments.



Quiz
Glossary
The glossary offers explanations of terminology used in the program.



Glossary
Tour manager
With the Tour Manager you can select a series of modules that you would like to "work through" consecutively. Quiz questions corresponding to the individual modules are asked at the end of the respective module. You can save different tours as files and access them again later.



Tours
Network capable
These CD-ROMs can not only be used on individual computers, but also in local area networks (LANs). The installation and operation of the "The Cell" CD-ROMs in a network is only permitted after the purchase of the appropriate licence. Multi-person licenses are available from Quelle & Meyer Verlag as classroom or network licences on request. Information and enquiries at: vertrieb@quelle-meyer.de


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Aug 9, 2007 , © IWF Wissen und Medien gGmbH, Nonnenstieg 72, D - 37075 Göttingen