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The Cell – The Powerplant
Mitochondrion and Catabolic Metabolism


System requirements:
  • Windows 95/98/ME/XP/2000/NT (4.0)
  • MacOS (8.1 or higher), MacOS X (only in Classic environment)
  • Price: 34,95 Euros (incl. VAT, countries other than Germany: + actual shipping costs + 5 Euros flat rate for service)
    Order: The English version can only be ordered directly from the IWF Knowledge and Media. Notice: Copies of the English version do not include an information booklet.
    The German version can be ordered over book shops (ISBN 3-494-01308-X) or by direct order at IWF Knowledge and Media.

    Mitochondria are the organelles in which the most important energy-providing catabolic processes take place. There, the energy obtained through nutrition is converted into an energy form usable by the cell. Mitochondria, the power plants of the cell, are found both in animal and in plant cells. In addition to 3D models and computer animations, photographs illustrate their structural and functional characteristics whilst employing special electron, light and laser microscopic techniques to provide depth to the presentation. A versatile and ingenious navigation system the programme provides three different routes for the user's journey through the mitochondrion.
    This second CD-ROM of the series about cell biology has been awarded the Digita 2002 for cinematographic excellence.


    Content

    Compass
    The compass, which you can access at all times, gives a complete overview of the content. There you find all topics and subjects which you can access and subsequently deal with.

    Compass
    Mitochondrion

    Function
    The complicated biochemical processes that make up cellular respiration are shown in an interactive animation. Steps in the degradation of fat, and storage substances as starch and glycogen, as well as fermentation and calcium regulation by mitochondria are vividly explained in detail.
    During an interactive computer animation related to the respiratory chain, the user is required to investigate where exactly toxins such as cyanide, rotenone, antimycin or FCCP launch their devastating attacks.
    Interactive animations present the details of the tricarboxylic-acid cycle.


    Structure
    3D models and EM-shots show the structure of mitochondria as well as the influence of ADP and ATP on the inner mitochondrial membrane. Video film demonstrations of living mitochondria, achieved by different recording techniques, give testimony to the highly dynamic nature of these cell organelles.

    Reproduction and protein import
    Light microscopical and EM shots demonstrate the cleavage and fusion of mitochondria, and the importation of proteins into the mitochondrion is explained by a computer animation.


    Cellular respiration

    Structure as related to function

    Tricarboxylic-acid cycle

    Respiratory-chain  


    EM shots


    Cytochrome-c oxidase



    Basic principles
    ATP and NAD
     

    ATP (Adenosine triphosphate) is the universal energy currency of the cell. NAD (Nicotinamide-adenine dinucleotide) functions as a redox reactant. The structure and function of these two important molecules in metabolism are shown in detail.


     


    ATP
    ATP-Synthase
     

    As a result of our co-operation with leading scientists the latest findings on the structure and function of the ATP-synthase molecule could be incorporated into our presentation. A 3D model illustrates how conformation changes and ATP production are related.



     


    ATP synthase
    Specialties
    Virtual lab: respiratory activity of mitochondria
    The oxygen consumption of mitochondria can be made visible in this interactive laboratory experiment. Which substrates do mitochondria need in order to be able to respire? Several substrate combinations can be tested.

    Films
    All the films of the learning program are listed and can be accessed individually.

    Quiz
    The Quiz gives you the opportunity to test your acquired knowledge on the function, structure and reproduction of mitochondria and the outcomes of the experiments.

    Glossary
    The glossary offers explanations of terminology used in the program.

    3D-lab
    In the 3D-Lab 3-D models of cells and molecules can be explored.



    Virtual Lab

    Films

    Quiz

    Glossary

    3D-Lab

    Network capable
    These CD-ROMs can not only be used on individual computers, but also in local area networks (LANs). The installation and operation of the "The Cell" CD-ROMs in a network is only permitted after the purchase of the appropriate licence. Multi-person licenses are available from Quelle & Meyer Verlag as classroom or network licences on request. Information and enquiries at: vertrieb@quelle-meyer.de


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